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Chemical structure of FHT-1204

GC64777

FHT-1204

Also known as N-[(2S)-3-methoxy-1-oxo-1-[[4-(3-pyridin-4-ylphenyl)-1,3-thiazol-2-yl]amino]propan-2-yl]-1-methylsulfonylpyrrole-3-carboxamide

FHT-1204 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 70)

ChemicalCAS2468048-24-8MW525.6FormulaC24H23N5O5S2
CAS number
2468048-24-8
Molecular weight
525.6
Formula
C24H23N5O5S2
InChIKey
AXMLAOCXALIIRY-FQEVSTJZSA-N
Catalogue number
GC64777
Brand
GLPBIO
Computed properties PubChem CID 154667935 · XLogP 2 · TPSA 169 Ų · H-bond donors 2
XLogP
2
TPSA
169 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
9
Heavy atoms
36

SMILES COC[C@@H](C(=O)NC1=NC(=CS1)C2=CC=CC(=C2)C3=CC=NC=C3)NC(=O)C4=CN(C=C4)S(=O)(=O)C

Computed descriptors from PubChem (CID 154667935), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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