Loading...
Chemical structure of Orismilast

GC64773

Orismilast

Also known as 2-(3,5-dichloro-1-oxidopyridin-1-ium-4-yl)-1-[7-(difluoromethoxy)-1',1'-dioxospiro[1,3-benzodioxole-2,4'-thiane]-4-yl]ethanone

Orismilast (LEO-32731) is a PDE4 inhibitor used for the research of inflammatory diseases

ChemicalCAS1353546-86-7MW510.29FormulaC19H15Cl2F2NO7S
CAS number
1353546-86-7
Molecular weight
510.29
Formula
C19H15Cl2F2NO7S
Solubility
DMSO ： 100 mg/mL (195·97 mM; Need ultrasonic)
InChIKey
ZININGNRPUGNSL-UHFFFAOYSA-N
Catalogue number
GC64773
Brand
GLPBIO
Computed properties PubChem CID 54765967 · XLogP 2.9 · TPSA 113 Ų · H-bond donors 0
XLogP
2.9
TPSA
113 Ų
H-bond donors
0
H-bond acceptors
9
Rotatable bonds
5
Heavy atoms
32

SMILES C1CS(=O)(=O)CCC12OC3=C(C=CC(=C3O2)OC(F)F)C(=O)CC4=C(C=[N+](C=C4Cl)[O-])Cl

Computed descriptors from PubChem (CID 54765967), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.