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Chemical structure of Etavopivat

GC64428

Etavopivat

Also known as (2S)-1-[5-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-7-ylsulfonyl)-1,3,4,6-tetrahydropyrrolo[3,4-c]pyrrol-2-yl]-3-hydroxy-2-phenylpropan-1-one

Etavopivat is a potent, selective, orally bioavailable red blood cell (RBC) pyruvate kinase (PKR) activator

ChemicalCAS2245053-57-8MW457.5FormulaC22H23N3O6S
CAS number
2245053-57-8
Molecular weight
457.5
Formula
C22H23N3O6S
Solubility
DMSO ： 50 mg/mL (109·29 mM; Need ultrasonic)
InChIKey
KZFFYEPYCVDOGE-LJQANCHMSA-N
Catalogue number
GC64428
Brand
GLPBIO
Computed properties PubChem CID 135338378 · XLogP -0.8 · TPSA 118 Ų · H-bond donors 1
XLogP
-0.8
TPSA
118 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
32

SMILES C1COC2=C(O1)C=C(C=N2)S(=O)(=O)N3CC4=C(C3)CN(C4)C(=O)[C@H](CO)C5=CC=CC=C5

Computed descriptors from PubChem (CID 135338378), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.