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Chemical structure of Tezacitabine

GC64373

Tezacitabine

Also known as 4-amino-1-[(2R,3E,4S,5R)-3-(fluoromethylidene)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

Tezacitabine is a cytostatic and cytotoxic antimetabolite and a nucleoside analogue· Tezacitabine irreversibly inhibits the ribonucleotide reductase and interferes with DNA replication and repair· Tezacitabine effectively induces cells apoptotic· Tezacitabine has the potential for leukemias and solid tumors (carcinomas) treatment

ChemicalCAS130306-02-4MW257.22FormulaC10H12FN3O4
CAS number
130306-02-4
Molecular weight
257.22
Formula
C10H12FN3O4
Solubility
DMSO ： 200 mg/mL (777·54 mM; Need ultrasonic)
InChIKey
GFFXZLZWLOBBLO-ASKVSEFXSA-N
Catalogue number
GC64373
Brand
GLPBIO
Computed properties PubChem CID 6435808 · XLogP -2.3 · TPSA 108 Ų · H-bond donors 3
XLogP
-2.3
TPSA
108 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
18

SMILES C1=CN(C(=O)N=C1N)[C@H]2/C(=C/F)/[C@@H]([C@H](O2)CO)O

Computed descriptors from PubChem (CID 6435808), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.