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Chemical structure of I-BET567

GC64297

I-BET567

Also known as (2S,4R)-1-acetyl-4-[(5-chloropyrimidin-2-yl)amino]-2-methyl-3,4-dihydro-2H-quinoline-6-carboxamide

I-BET567 is a potent and orally active inhibitor of pan-BET candidate with pIC50s of 6·9 and 7·2 for BRD4 BD1 and BD2, respectively

ChemicalCAS1887237-54-8MW359.81FormulaC17H18ClN5O2
CAS number
1887237-54-8
Molecular weight
359.81
Formula
C17H18ClN5O2
Solubility
DMSO ： 100 mg/mL (277·92 mM; Need ultrasonic)
InChIKey
KNBYFXZNSOENGW-LKFCYVNXSA-N
Catalogue number
GC64297
Brand
GLPBIO
Computed properties PubChem CID 118948181 · XLogP 1.5 · TPSA 101 Ų · H-bond donors 2
XLogP
1.5
TPSA
101 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
25

SMILES C[C@H]1C[C@H](C2=C(N1C(=O)C)C=CC(=C2)C(=O)N)NC3=NC=C(C=N3)Cl

Computed descriptors from PubChem (CID 118948181), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.