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Chemical structure of AMXI-5001

GC64273

AMXI-5001

Also known as ethyl N-[6-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]phenyl]-1H-benzimidazol-2-yl]carbamate

AMXI-5001 is a potent, orally active, and dual parp1/2 and microtubule polymerization inhibitor· MXI-5001 exhibits selective antitumor cytotoxicity across a wide variety of human cancer cells with much lower IC50s than existing clinical PARP1/2 inhibitors· AMXI-5001 induces complete regression of established tumors, including exceedingly large tumors

ChemicalCAS2170491-77-5MW457.46FormulaC25H20FN5O3
CAS number
2170491-77-5
Molecular weight
457.46
Formula
C25H20FN5O3
InChIKey
DCSUGHIXMFUMOQ-UHFFFAOYSA-N
Catalogue number
GC64273
Brand
GLPBIO
Computed properties PubChem CID 145426155 · XLogP 4.2 · TPSA 108 Ų · H-bond donors 3
XLogP
4.2
TPSA
108 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
34

SMILES CCOC(=O)NC1=NC2=C(N1)C=C(C=C2)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F

Computed descriptors from PubChem (CID 145426155), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.