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Chemical structure of 1-Cbz-3-Hydroxyazetidine

GC64145

1-Cbz-3-Hydroxyazetidine

Also known as benzyl 3-hydroxyazetidine-1-carboxylate

1-Cbz-3-Hydroxyazetidine is a non-cleavable?ADC linker?used in the synthesis of antibody-drug conjugates (ADCs)· 1-Cbz-3-Hydroxyazetidine is also a alkyl chain-based PROTAC linker?that can be used in the synthesis of PROTACs

ChemicalCAS128117-22-6MW207.23FormulaC11H13NO3
CAS number
128117-22-6
Molecular weight
207.23
Formula
C11H13NO3
InChIKey
XJWSNDGCJMGHSR-UHFFFAOYSA-N
Catalogue number
GC64145
Brand
GLPBIO
Computed properties PubChem CID 10081755 · XLogP 0.8 · TPSA 49.8 Ų · H-bond donors 1
XLogP
0.8
TPSA
49.8 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
15

SMILES C1C(CN1C(=O)OCC2=CC=CC=C2)O

Computed descriptors from PubChem (CID 10081755), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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