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Chemical structure of RECQL5-IN-1

GC64100

RECQL5-IN-1

Also known as 1-[(S)-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)-phenylmethyl]-3-[3,5-bis(trifluoromethyl)phenyl]urea

RECQL5-IN-1 (Compound 4a) acts as an orally effective RECQL5 inhibitor (targeting both enzymatic and nonenzymatic domain)· RECQL5-IN-1 is a potent inhibitor of RECQL5 helicase activity (IC50=46·3 nM)· RECQL5-IN-1 inhibits RECQL5-WT cells and RECQL5-KO2 cells with IC50s of 4·8 μM and 19·6 μM, respectively· RECQL5-IN-1 can be used for the research of breast cancer

ChemicalCAS2718170-45-5MW552.49FormulaC25H18F6N4O2S
CAS number
2718170-45-5
Molecular weight
552.49
Formula
C25H18F6N4O2S
InChIKey
BHTXRKYKSWDTRG-FQEVSTJZSA-N
Catalogue number
GC64100
Brand
GLPBIO
Computed properties PubChem CID 163196444 · XLogP 6.1 · TPSA 105 Ų · H-bond donors 2
XLogP
6.1
TPSA
105 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
38

SMILES C1=CC=C(C=C1)CSC2=NN=C(O2)[C@H](C3=CC=CC=C3)NC(=O)NC4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F

Computed descriptors from PubChem (CID 163196444), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.