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Chemical structure of cis-4-Hydroxy-D-proline hydrochloride

GC64093

cis-4-Hydroxy-D-proline hydrochloride

Also known as (2R,4R)-4-hydroxypyrrolidine-2-carboxylic acid;hydrochloride

cis-4-Hydroxy-D-proline hydrochloride is a non-cleavable?ADC linker?used in the synthesis of antibody-drug conjugates (ADCs)· cis-4-Hydroxy-D-proline hydrochloride is also a alkyl chain-based PROTAC linker?that can be used in the synthesis of PROTACs

ChemicalCAS77449-94-6MW167.59FormulaC5H10ClNO3
CAS number
77449-94-6
Molecular weight
167.59
Formula
C5H10ClNO3
InChIKey
YEJFFQAGTXBSTI-VKKIDBQXSA-N
Catalogue number
GC64093
Brand
GLPBIO
Computed properties PubChem CID 12310682 · TPSA 69.6 Ų · H-bond donors 4 · H-bond acceptors 4
TPSA
69.6 Ų
H-bond donors
4
H-bond acceptors
4
Rotatable bonds
1
Heavy atoms
10

SMILES C1[C@H](CN[C@H]1C(=O)O)O.Cl

Computed descriptors from PubChem (CID 12310682), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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