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Chemical structure of 1-Cbz-azetidine-3-carboxylic acid

GC64047

1-Cbz-azetidine-3-carboxylic acid

Also known as 1-phenylmethoxycarbonylazetidine-3-carboxylic acid

1-Cbz-azetidine-3-carboxylic acid is a non-cleavable?ADC linker?used in the synthesis of antibody-drug conjugates (ADCs)· 1-Cbz-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker?that can be used in the synthesis of PROTACs

ChemicalCAS97628-92-7MW235.24FormulaC12H13NO4
CAS number
97628-92-7
Molecular weight
235.24
Formula
C12H13NO4
InChIKey
PVJPBKZGIUAESY-UHFFFAOYSA-N
Catalogue number
GC64047
Brand
GLPBIO
Computed properties PubChem CID 10988214 · XLogP 0.9 · TPSA 66.8 Ų · H-bond donors 1
XLogP
0.9
TPSA
66.8 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
17

SMILES C1C(CN1C(=O)OCC2=CC=CC=C2)C(=O)O

Computed descriptors from PubChem (CID 10988214), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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