Loading...
Chemical structure of KL-11743

GC64014

KL-11743

Also known as 2-[3-[6-ethoxy-4-[4-(1H-pyrazol-4-yl)anilino]quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide

KL-11743 is a potent, orally active, and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90, and 68 nM for GLUT1, GLUT2, GLUT3, and GLUT4, respectively

ChemicalCAS1369452-53-8MW522.6FormulaC30H30N6O3
CAS number
1369452-53-8
Molecular weight
522.6
Formula
C30H30N6O3
Solubility
DMSO ： 25 mg/mL (47·84 mM; ultrasonic and warming and heat to 60°C)
InChIKey
XKOYTLRGOQTKAU-UHFFFAOYSA-N
Catalogue number
GC64014
Brand
GLPBIO
Computed properties PubChem CID 146345838 · XLogP 5.5 · TPSA 114 Ų · H-bond donors 3
XLogP
5.5
TPSA
114 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
10
Heavy atoms
39

SMILES CCOC1=CC2=C(C=C1)N=C(N=C2NC3=CC=C(C=C3)C4=CNN=C4)C5=CC(=CC=C5)OCC(=O)NC(C)C

Computed descriptors from PubChem (CID 146345838), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.