
GC63924
Boc-C16-COOH
Also known as 18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoic acid
Boc-C16-COOH is a non-cleavable?ADC linker?used in the synthesis of antibody-drug conjugates (ADCs)· Boc-C16-COOH is also a alkyl chain-based PROTAC linker?that can be used in the synthesis of PROTACs<su PROTAC KRAS G12C degrader-199·55%PROTAC KRAS G12C degrader-1 is a Cereblon-based KRASG12C degrader, with an IC50 of 414 nM for CRBN· PROTAC KRAS G12C degrader-1 induces CRBN/ KRASG12C dimerization and degrades GFP- KRASG12C in reporter cells
ChemicalCAS843666-40-0MW370.57FormulaC22H42O4
- CAS number
- 843666-40-0
- Molecular weight
- 370.57
- Formula
- C22H42O4
- InChIKey
- WDUQJXKBWRNMKI-UHFFFAOYSA-N
- Catalogue number
- GC63924
- Brand
- GLPBIO
Computed properties PubChem CID 27282473 · XLogP 7.7 · TPSA 63.6 Ų · H-bond donors 1
- XLogP
- 7.7
- TPSA
- 63.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Rotatable bonds
- 19
- Heavy atoms
- 26
SMILES CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(=O)O
Computed descriptors from PubChem (CID 27282473), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il