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Chemical structure of Abemaciclib metabolite M18 hydrochloride

GC63728

Abemaciclib metabolite M18 hydrochloride

Abemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib, is a CDK inhibitor with antitumor activity· Abemaciclib metabolite M18 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader

ChemicalMW531FormulaC25H29ClF2N8O
CAS number
Molecular weight
531
Formula
C25H29ClF2N8O
Solubility
DMSO : 125 mg/mL (235·40 mM; Need ultrasonic)|Water : 100 mg/mL (188·32 mM; Need ultrasonic)
Catalogue number
GC63728
Brand
GLPBIO

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