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Chemical structure of UK122

GC63693

UK122

Also known as 4-[(E)-(5-oxo-2-phenyl-1,3-oxazol-4-ylidene)methyl]benzenecarboximidamide

UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0·2 μM· UK122 shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50>100 μM)· UK122, 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion

ChemicalCAS940290-58-4MW291.3FormulaC17H13N3O2
CAS number
940290-58-4
Molecular weight
291.3
Formula
C17H13N3O2
InChIKey
JBHISGPWLXASFE-GXDHUFHOSA-N
Catalogue number
GC63693
Brand
GLPBIO
Computed properties PubChem CID 16220264 · XLogP 2.5 · TPSA 88.5 Ų · H-bond donors 2
XLogP
2.5
TPSA
88.5 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
22

SMILES C1=CC=C(C=C1)C2=N/C(=C/C3=CC=C(C=C3)C(=N)N)/C(=O)O2

Computed descriptors from PubChem (CID 16220264), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.