Loading...
Chemical structure of DHODH-IN-16

GC63547

DHODH-IN-16

Also known as 6-[4-ethyl-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-7-fluoro-2-(2-methylphenyl)-4-propan-2-ylisoquinolin-1-one

DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0·396 nM for human DHODH

ChemicalCAS2511248-11-4MW436.48FormulaC24H25FN4O3
CAS number
2511248-11-4
Molecular weight
436.48
Formula
C24H25FN4O3
Solubility
DMSO ： 100 mg/mL (229·11 mM; Need ultrasonic)
InChIKey
BZKHQYHQHLKJNX-UHFFFAOYSA-N
Catalogue number
GC63547
Brand
GLPBIO
Computed properties PubChem CID 155209570 · XLogP 3.1 · TPSA 76.5 Ų · H-bond donors 1
XLogP
3.1
TPSA
76.5 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
32

SMILES CCN1C(=NN(C1=O)C2=C(C=C3C(=C2)C(=CN(C3=O)C4=CC=CC=C4C)C(C)C)F)CO

Computed descriptors from PubChem (CID 155209570), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.