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Chemical structure of Reverse transcriptase-IN-1

GC63523

Reverse transcriptase-IN-1

Also known as 4-[[4-[4-[(E)-2-cyanoethenyl]-2-methyl-6-nitroanilino]quinazolin-2-yl]amino]benzonitrile

Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor

ChemicalCAS2380001-43-2MW447.45FormulaC25H17N7O2
CAS number
2380001-43-2
Molecular weight
447.45
Formula
C25H17N7O2
Solubility
DMSO ： 12·5 mg/mL (27·94 mM; ultrasonic and warming and heat to 60°C)
InChIKey
MNZKGXAFXCQSCG-SNAWJCMRSA-N
Catalogue number
GC63523
Brand
GLPBIO
Computed properties PubChem CID 139600333 · XLogP 5.9 · TPSA 143 Ų · H-bond donors 2
XLogP
5.9
TPSA
143 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
34

SMILES CC1=CC(=CC(=C1NC2=NC(=NC3=CC=CC=C32)NC4=CC=C(C=C4)C#N)[N+](=O)[O-])/C=C/C#N

Computed descriptors from PubChem (CID 139600333), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.