GC63507
HM43239
HM43239 is an orally active and selective FLT3 inhibitor with IC50s of 1·1 nM, 1·8 nM and 1·0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively· HM43239 inhibits the kinase activity of FLT3 as a reversible type I inhibitor and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1· HM43239 inhibits the proliferation and induces the apoptosis of leukemic cells
ChemicalMW501.07FormulaC29H33ClN6
- CAS number
- —
- Molecular weight
- 501.07
- Formula
- C29H33ClN6
- Solubility
- DMSO ： 125 mg/mL (249·47 mM; Need ultrasonic)
- Catalogue number
- GC63507
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il