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Chemical structure of VB124

GC63496

VB124

Also known as 2-[[1-(2-chlorophenyl)-5-(3-cyclopropyloxyphenyl)pyrazol-3-yl]methoxy]-2-methylpropanoic acid

VB124 is a safe, effective and orally active selective monocarboxylate transport protein 4(MCT4) inhibitor· VB124 blocks the input (IC50 = 8·6nM) and output (IC50 = 19nm) of lactic acid in MDA-MB-231 cells

ChemicalCAS2230186-18-0MW426.89FormulaC23H23ClN2O4
CAS number
2230186-18-0
Molecular weight
426.89
Formula
C23H23ClN2O4
Solubility
DMSO ： 100 mg/mL (234·25 mM; Need ultrasonic)
InChIKey
PZHRLEZWTVYGMP-UHFFFAOYSA-N
Catalogue number
GC63496
Brand
GLPBIO
Computed properties PubChem CID 134602985 · XLogP 4.6 · TPSA 73.6 Ų · H-bond donors 1
XLogP
4.6
TPSA
73.6 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
8
Heavy atoms
30

SMILES CC(C)(C(=O)O)OCC1=NN(C(=C1)C2=CC(=CC=C2)OC3CC3)C4=CC=CC=C4Cl

Computed descriptors from PubChem (CID 134602985), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.