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Chemical structure of Rimtuzalcap

GC63482

Rimtuzalcap

Also known as N-(4,4-difluorocyclohexyl)-2-(3-methylpyrazol-1-yl)-6-morpholin-4-ylpyrimidin-4-amine

Rimtuzalcap (CAD-1883) is a first-in-class selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels)

ChemicalCAS2167246-24-2MW378.42FormulaC18H24F2N6O
CAS number
2167246-24-2
Molecular weight
378.42
Formula
C18H24F2N6O
Solubility
DMSO : 250 mg/mL (660·64 mM; Need ultrasonic)
InChIKey
OVLIDRAJVMUEMC-UHFFFAOYSA-N
Catalogue number
GC63482
Brand
GLPBIO
Computed properties PubChem CID 132207249 · XLogP 3.2 · TPSA 68.1 Ų · H-bond donors 1
XLogP
3.2
TPSA
68.1 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
27

SMILES CC1=NN(C=C1)C2=NC(=CC(=N2)N3CCOCC3)NC4CCC(CC4)(F)F

Computed descriptors from PubChem (CID 132207249), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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