GC63456
Seclidemstat mesylate
Also known as N-[(E)-1-(5-chloro-2-hydroxyphenyl)ethylideneamino]-3-(4-methylpiperazin-1-yl)sulfonylbenzamide;methanesulfonic acid
Seclidemstat (SP-2577) mesylate is a potent noncompetitive and reversible KDM1A (LSD1) inhibitor (Ki=31 nM, IC50=13 nM)· Seclidemstat mesylate promotes antitumor immunity in switch/sucrose nonfermentable (SWI/SNF) complex mutated ovarian cancer, as well as inhibit virus production, viral DNA replication, and late gene expression· Seclidemstat mesylate can be used for the research of Ewing Sarcoma
- CAS number
- 2044953-70-8
- Molecular weight
- 547.04
- Formula
- C21H27ClN4O7S2
- Solubility
- DMSO ： 53·33 mg/mL (97·49 mM; Need ultrasonic)
- InChIKey
- JIPBQMGGMHCGBW-CWUUNJJBSA-N
- Catalogue number
- GC63456
- Brand
- GLPBIO
Computed properties PubChem CID 135565032 · TPSA 173 Ų · H-bond donors 3 · H-bond acceptors 10
- TPSA
- 173 Ų
- H-bond donors
- 3
- H-bond acceptors
- 10
- Rotatable bonds
- 5
- Heavy atoms
- 35
SMILES C/C(=N\NC(=O)C1=CC(=CC=C1)S(=O)(=O)N2CCN(CC2)C)/C3=C(C=CC(=C3)Cl)O.CS(=O)(=O)O
Computed descriptors from PubChem (CID 135565032), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il