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Chemical structure of Avotaciclib

GC63449

Avotaciclib

Also known as 2,6-bis(2-aminopyrimidin-4-yl)pyridin-3-ol

Avotaciclib (BEY1107) is a potent and orally active inhibitor of cyclin dependent kinase 1 (CDK1)· Avotaciclib can be used for the research of locally advanced or metastatic pancreatic cancer

ChemicalCAS1983983-41-0MW281.27FormulaC13H11N7O
CAS number
1983983-41-0
Molecular weight
281.27
Formula
C13H11N7O
InChIKey
VFVAQKKPFOPZEA-UHFFFAOYSA-N
Catalogue number
GC63449
Brand
GLPBIO
Computed properties PubChem CID 137150099 · XLogP -0.2 · TPSA 137 Ų · H-bond donors 3
XLogP
-0.2
TPSA
137 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
2
Heavy atoms
21

SMILES C1=CC(=NC(=C1O)C2=NC(=NC=C2)N)C3=NC(=NC=C3)N

Computed descriptors from PubChem (CID 137150099), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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