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Chemical structure of LTA4H-IN-1

GC63435

LTA4H-IN-1

Also known as (3S)-3-amino-4-[5-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenyl]tetrazol-2-yl]butanoic acid

LTA4H-IN-1 is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) extracted from patent WO2015092740A1, example 29, has an IC50 of 2 nM

ChemicalCAS1799681-85-8MW392.77FormulaC16H14ClFN6O3
CAS number
1799681-85-8
Molecular weight
392.77
Formula
C16H14ClFN6O3
Solubility
DMSO ： 250 mg/mL (636·50 mM; Need ultrasonic)
InChIKey
ZEGMEJVULDALSH-NSHDSACASA-N
Catalogue number
GC63435
Brand
GLPBIO
Computed properties PubChem CID 118166560 · XLogP -0.4 · TPSA 129 Ų · H-bond donors 2
XLogP
-0.4
TPSA
129 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
27

SMILES C1=CC(=CC=C1C2=NN(N=N2)C[C@H](CC(=O)O)N)OC3=C(C=C(C=N3)Cl)F

Computed descriptors from PubChem (CID 118166560), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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