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Chemical structure of CXCR7 antagonist-1

GC63411

CXCR7 antagonist-1

Also known as 1-(4-fluorophenyl)-N-[(3S)-1-pyrrolo[1,2-a]pyrazin-1-ylpyrrolidin-3-yl]pyrazole-3-carboxamide

CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7

ChemicalCAS1613021-99-0MW390.41FormulaC21H19FN6O
CAS number
1613021-99-0
Molecular weight
390.41
Formula
C21H19FN6O
InChIKey
IGJCDMUXCOCMMI-INIZCTEOSA-N
Catalogue number
GC63411
Brand
GLPBIO
Computed properties PubChem CID 90192074 · XLogP 3.5 · TPSA 67.5 Ų · H-bond donors 1
XLogP
3.5
TPSA
67.5 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
29

SMILES C1CN(C[C@H]1NC(=O)C2=NN(C=C2)C3=CC=C(C=C3)F)C4=NC=CN5C4=CC=C5

Computed descriptors from PubChem (CID 90192074), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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