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Chemical structure of AZD-4818

GC63284

AZD-4818

Also known as 2-[2-chloro-5-[(2S)-3-(5-chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-(methylcarbamoyl)phenoxy]-2-methylpropanoic acid

AZD-4818 is a potent antagonist of chemokine CCR1

ChemicalCAS1003566-93-5MW567.46FormulaC27H32Cl2N2O7
CAS number
1003566-93-5
Molecular weight
567.46
Formula
C27H32Cl2N2O7
Solubility
DMSO : 50 mg/mL (88·11 mM; ultrasonic and adjust pH to 2 with HCl)
InChIKey
HVTUHSABWJPWNK-SFHVURJKSA-N
Catalogue number
GC63284
Brand
GLPBIO
Computed properties PubChem CID 24955007 · XLogP 1.8 · TPSA 118 Ų · H-bond donors 3
XLogP
1.8
TPSA
118 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
9
Heavy atoms
38

SMILES CC(C)(C(=O)O)OC1=C(C=C(C(=C1)OC[C@H](CN2CCC3(CC2)CC4=C(O3)C=CC(=C4)Cl)O)C(=O)NC)Cl

Computed descriptors from PubChem (CID 24955007), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.