GC63212
TBK1/IKKε-IN-4
Also known as N-[3,4-dimethoxy-5-[3-(4-methylpiperazin-1-yl)propoxy]phenyl]-1-(4-methoxyphenyl)pyrazolo[3,4-d]pyrimidin-6-amine
TBK1/IKKε-IN-4 is a 6-aminopyrazolopyrimidine derivative and a potent, selective TBK1 and IKKε inhibitor with IC50 values of 13 nM and 59 nM, respectively· TBK1/IKKε-IN-4 shows 100- to 1000-fold less activity against other protein kinases including PDK1, PI3K family members and mTOR
ChemicalCAS1381930-17-1MW533.62FormulaC28H35N7O4
- CAS number
- 1381930-17-1
- Molecular weight
- 533.62
- Formula
- C28H35N7O4
- Solubility
- DMSO ： 70 mg/mL (131·18 mM; Need ultrasonic)
- InChIKey
- PVQUVXVUIZZLMP-UHFFFAOYSA-N
- Catalogue number
- GC63212
- Brand
- GLPBIO
Computed properties PubChem CID 121230617 · XLogP 3.8 · TPSA 99 Ų · H-bond donors 1
- XLogP
- 3.8
- TPSA
- 99 Ų
- H-bond donors
- 1
- H-bond acceptors
- 10
- Rotatable bonds
- 11
- Heavy atoms
- 39
SMILES CN1CCN(CC1)CCCOC2=CC(=CC(=C2OC)OC)NC3=NC=C4C=NN(C4=N3)C5=CC=C(C=C5)OC
Computed descriptors from PubChem (CID 121230617), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il