Loading...
Chemical structure of SM-433

GC63195

SM-433

Also known as (5S,8S,10aR)-5-[[(2S)-2-(methylamino)propanoyl]amino]-3-(3-methylbutanoyl)-6-oxo-N-[(2-phenylphenyl)methyl]-1,2,4,5,8,9,10,10a-octahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide

SM-433, a Smac mimetic, function as inhibitor of inhibitor of apoptosis proteins (IAPs)· SM-433 exhibits strong binding affinity XIAP BIR3 protein with an IC50＜1 μM (patent WO2008128171A2)

ChemicalCAS1071992-81-8MW561.71FormulaC32H43N5O4
CAS number
1071992-81-8
Molecular weight
561.71
Formula
C32H43N5O4
InChIKey
SZVCBOBNBHXZKC-MZRLSVQCSA-N
Catalogue number
GC63195
Brand
GLPBIO
Computed properties PubChem CID 25173585 · XLogP 3.1 · TPSA 111 Ų · H-bond donors 3
XLogP
3.1
TPSA
111 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
9
Heavy atoms
41

SMILES C[C@@H](C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NCC3=CC=CC=C3C4=CC=CC=C4)C(=O)CC(C)C)NC

Computed descriptors from PubChem (CID 25173585), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.