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Chemical structure of RO5263397

GC63174

RO5263397

Also known as (4S)-4-(3-fluoro-2-methylphenyl)-4,5-dihydro-1,3-oxazol-2-amine

RO5263397 is a potent, selective, and orally available TAAR1 agonist, with EC50s of 17 and 35 nM for human TAAR1 and rat TAAR1, respectively

ChemicalCAS1357266-05-7MW194.21FormulaC10H11FN2O
CAS number
1357266-05-7
Molecular weight
194.21
Formula
C10H11FN2O
Solubility
DMSO ： 260 mg/mL (1338·76 mM; Need ultrasonic)
InChIKey
IOHOUWIYOVWGHV-SECBINFHSA-N
Catalogue number
GC63174
Brand
GLPBIO
Computed properties PubChem CID 56835991 · XLogP 1.4 · TPSA 47.6 Ų · H-bond donors 1
XLogP
1.4
TPSA
47.6 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
1
Heavy atoms
14

SMILES CC1=C(C=CC=C1F)[C@H]2COC(=N2)N

Computed descriptors from PubChem (CID 56835991), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.