Loading...
Chemical structure of MRGPRX1 agonist 1

GC63078

MRGPRX1 agonist 1

Also known as N-[2-(1-aminoisoquinolin-6-yl)oxy-4-methylphenyl]-2-methoxybenzenesulfonamide

MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1), with an EC50 of 50 nM, and is inactive on MRGPRC11

ChemicalCAS2377379-39-8MW435.5FormulaC23H21N3O4S
CAS number
2377379-39-8
Molecular weight
435.5
Formula
C23H21N3O4S
Solubility
DMSO ： 130 mg/mL (298·51 mM; Need ultrasonic)
InChIKey
BWEJNHRMGZUMNU-UHFFFAOYSA-N
Catalogue number
GC63078
Brand
GLPBIO
Computed properties PubChem CID 139030531 · XLogP 4.1 · TPSA 112 Ų · H-bond donors 2
XLogP
4.1
TPSA
112 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
31

SMILES CC1=CC(=C(C=C1)NS(=O)(=O)C2=CC=CC=C2OC)OC3=CC4=C(C=C3)C(=NC=C4)N

Computed descriptors from PubChem (CID 139030531), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.