GC63056
MAK683-CH2CH2COOH
Also known as 3-[5-[5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl]-6-methyl-2-pyridinyl]propanoic acid
MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein)· MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 and PROTAC EED degrader-2
ChemicalCAS2639882-68-9MW448.45FormulaC23H21FN6O3
- CAS number
- 2639882-68-9
- Molecular weight
- 448.45
- Formula
- C23H21FN6O3
- InChIKey
- WWNHSPXQGRANDX-UHFFFAOYSA-N
- Catalogue number
- GC63056
- Brand
- GLPBIO
Computed properties PubChem CID 146014470 · XLogP 3.2 · TPSA 115 Ų · H-bond donors 2
- XLogP
- 3.2
- TPSA
- 115 Ų
- H-bond donors
- 2
- H-bond acceptors
- 9
- Rotatable bonds
- 7
- Heavy atoms
- 33
SMILES CC1=C(C=CC(=N1)CCC(=O)O)C2=CN=C(N3C2=NN=C3)NCC4=C(C=CC5=C4CCO5)F
Computed descriptors from PubChem (CID 146014470), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il