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Chemical structure of HWL-088

GC63010

HWL-088

Also known as 2-[2-fluoro-4-[[3-(2-methylphenyl)phenyl]methoxy]phenoxy]acetic acid

HWL-088 is a highly potent and orally active free fatty acid receptor 1 (FFA1/GPR40) agonist (EC50 of 18·9 nM) with moderate PPARδ activity (EC50 of 570·9 nM)

ChemicalCAS2378617-96-8MW366.38FormulaC22H19FO4
CAS number
2378617-96-8
Molecular weight
366.38
Formula
C22H19FO4
Solubility
DMSO : 250 mg/mL (682·35 mM; Need ultrasonic)
InChIKey
NJYJBYPNDWNZAH-UHFFFAOYSA-N
Catalogue number
GC63010
Brand
GLPBIO
Computed properties PubChem CID 139600331 · XLogP 5 · TPSA 55.8 Ų · H-bond donors 1
XLogP
5
TPSA
55.8 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
27

SMILES CC1=CC=CC=C1C2=CC=CC(=C2)COC3=CC(=C(C=C3)OCC(=O)O)F

Computed descriptors from PubChem (CID 139600331), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.