GC62947
DYRKs-IN-1 hydrochloride
Also known as N-[5-[(3-amino-1-phenylpropyl)carbamoyl]-2-chlorophenyl]-2-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-7-oxo-8H-pyrido[2,3-d]pyrimidine-6-carboxamide;hydrochloride
DYRKs-IN-1 hydrochloride is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 5 nM and 8 nM for DYRK1A and DYRK1B, respectively· DYRKs-IN-1 hydrochloride has antitumor activity
ChemicalCAS1386980-55-7MW624.52FormulaC30H31Cl2N7O4
- CAS number
- 1386980-55-7
- Molecular weight
- 624.52
- Formula
- C30H31Cl2N7O4
- Solubility
- DMSO ： 20·83 mg/mL (33·35 mM; ultrasonic and warming and heat to 60°C)
- InChIKey
- XLHHYTUBPOMTDK-UHFFFAOYSA-N
- Catalogue number
- GC62947
- Brand
- GLPBIO
Computed properties PubChem CID 144416250 · TPSA 152 Ų · H-bond donors 5 · H-bond acceptors 8
- TPSA
- 152 Ų
- H-bond donors
- 5
- H-bond acceptors
- 8
- Rotatable bonds
- 8
- Heavy atoms
- 43
SMILES C1CC2CN(CC1O2)C3=NC=C4C=C(C(=O)NC4=N3)C(=O)NC5=C(C=CC(=C5)C(=O)NC(CCN)C6=CC=CC=C6)Cl.Cl
Computed descriptors from PubChem (CID 144416250), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il