Loading...
Chemical structure of CVN424

GC62915

CVN424

Also known as 1-[2-[4-(2,4-difluorophenoxy)piperidin-1-yl]-3-[[(3R)-oxolan-3-yl]amino]-7,8-dihydro-5H-pyrido[3,4-b]pyrazin-6-yl]ethanone

CVN424 is an orally active and selective GPR6 inverse agonist with a Ki of 9·4 nM and an EC50 of 38 nM

ChemicalCAS2254706-21-1MW473.52FormulaC24H29F2N5O3
CAS number
2254706-21-1
Molecular weight
473.52
Formula
C24H29F2N5O3
Solubility
DMSO ： 62·5 mg/mL (131·99 mM; Need ultrasonic)
InChIKey
HSWVJQBEXRKOBZ-QGZVFWFLSA-N
Catalogue number
GC62915
Brand
GLPBIO
Computed properties PubChem CID 137359492 · XLogP 2.4 · TPSA 79.8 Ų · H-bond donors 1
XLogP
2.4
TPSA
79.8 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
5
Heavy atoms
34

SMILES CC(=O)N1CCC2=C(C1)N=C(C(=N2)N3CCC(CC3)OC4=C(C=C(C=C4)F)F)N[C@@H]5CCOC5

Computed descriptors from PubChem (CID 137359492), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.