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Chemical structure of Berotralstat

GC62865

Berotralstat

Also known as 1-[3-(aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-3-(trifluoromethyl)pyrazole-5-carboxamide

Berotralstat (BCX7353) is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks

ChemicalCAS1809010-50-1MW562.56FormulaC30H26F4N6O
CAS number
1809010-50-1
Molecular weight
562.56
Formula
C30H26F4N6O
Solubility
DMSO ： 100 mg/mL (177·76 mM; Need ultrasonic)
InChIKey
UXNXMBYCBRBRFD-MUUNZHRXSA-N
Catalogue number
GC62865
Brand
GLPBIO
Computed properties PubChem CID 137528262 · XLogP 4.5 · TPSA 109 Ų · H-bond donors 3
XLogP
4.5
TPSA
109 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
9
Heavy atoms
41

SMILES C1CC1CN[C@@H](C2=CC(=C(C=C2)F)NC(=O)C3=CC(=NN3C4=CC=CC(=C4)CN)C(F)(F)F)C5=CC=CC(=C5)C#N

Computed descriptors from PubChem (CID 137528262), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.