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Chemical structure of 3-Demethylcolchicine

GC62794

3-Demethylcolchicine

Also known as N-[(7S)-3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide

3-Demethylcolchicine, a colchicine metabolite, possesses a hydroxy-group on its carbon ring that could participate in radical scavenging and markedly inhibits the carrageenin edema

ChemicalCAS7336-33-6MW385.41FormulaC21H23NO6
CAS number
7336-33-6
Molecular weight
385.41
Formula
C21H23NO6
Solubility
DMSO : 100 mg/mL (259·46 mM; Need ultrasonic)
InChIKey
JRRUSQGIRBEMRN-HNNXBMFYSA-N
Catalogue number
GC62794
Brand
GLPBIO
Computed properties PubChem CID 299664 · XLogP 0.7 · TPSA 94.1 Ų · H-bond donors 2
XLogP
0.7
TPSA
94.1 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
28

SMILES CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)O

Computed descriptors from PubChem (CID 299664), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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