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Chemical structure of (R)-Pirtobrutinib

GC62742

(R)-Pirtobrutinib

Also known as 5-amino-3-[4-[[(5-fluoro-2-methoxybenzoyl)amino]methyl]phenyl]-1-[(2R)-1,1,1-trifluoropropan-2-yl]pyrazole-4-carboxamide

(R)-Pirtobrutinib ((R)-LOXO-305) is a less active enantiomer of Pirtobrutinib

ChemicalCAS2101700-14-3MW479.43FormulaC22H21F4N5O3
CAS number
2101700-14-3
Molecular weight
479.43
Formula
C22H21F4N5O3
Solubility
DMSO : 200 mg/mL (417·16 mM; Need ultrasonic)
InChIKey
FWZAWAUZXYCBKZ-LLVKDONJSA-N
Catalogue number
GC62742
Brand
GLPBIO
Computed properties PubChem CID 129269918 · XLogP 3.3 · TPSA 125 Ų · H-bond donors 3
XLogP
3.3
TPSA
125 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
34

SMILES C[C@H](C(F)(F)F)N1C(=C(C(=N1)C2=CC=C(C=C2)CNC(=O)C3=C(C=CC(=C3)F)OC)C(=O)N)N

Computed descriptors from PubChem (CID 129269918), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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