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Chemical structure of Milademetan tosylate hydrate

GC62621

Milademetan tosylate hydrate

Milademetan (DS-3032) tosylate hydrate is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors· Milademetan (DS-3032) tosylate hydrate induces G1 cell cycle arrest, senescence and apoptosis

ChemicalCAS2095625-97-9MW808.74FormulaC37H44Cl2FN5O8S
CAS number
2095625-97-9
Molecular weight
808.74
Formula
C37H44Cl2FN5O8S
Solubility
DMSO : 200 mg/mL (247·30 mM; Need ultrasonic)
InChIKey
WPJOGWGXMTUHPW-CIPNXXNHSA-N
Catalogue number
GC62621
Brand
GLPBIO
Computed properties PubChem CID 89051550 · TPSA 199 Ų · H-bond donors 6 · H-bond acceptors 11
TPSA
199 Ų
H-bond donors
6
H-bond acceptors
11
Rotatable bonds
5
Heavy atoms
54

SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CC1(CCC2(CC1)[C@@]3([C@H]([C@@H](N2)C(=O)N[C@@H]4CC[C@H](OC4)C(=O)N)C5=C(C(=NC=C5)Cl)F)C6=C(C=C(C=C6)Cl)NC3=O)C.O

Computed descriptors from PubChem (CID 89051550), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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