GC62620
NHWD-870
Also known as 5-(3,5-dimethyltriazol-4-yl)-12-methyl-8-[(S)-oxan-4-yl(phenyl)methyl]-3,8,12,13-tetrazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2(7),3,5,10,13,15-heptaene
NHWD-870 is a potent, orally active and selective BET family bromodomain inhibitor and only binds bromodomains of BRD2, BRD3, BRD4 (IC50=2·7 nM), and BRDT· NHWD-870 has potent tumor suppressive efficacies and suppresses cancer cell-macrophage interaction· NHWD-870 increases tumor apoptosis and inhibits tumor proliferation
ChemicalCAS2115742-03-3MW491.59FormulaC29H29N7O
- CAS number
- 2115742-03-3
- Molecular weight
- 491.59
- Formula
- C29H29N7O
- Solubility
- DMSO ： 125 mg/mL (254·28 mM; Need ultrasonic)
- InChIKey
- YMSCCGUMGIFOSI-GDLZYMKVSA-N
- Catalogue number
- GC62620
- Brand
- GLPBIO
Computed properties PubChem CID 137448679 · XLogP 4.1 · TPSA 75.6 Ų · H-bond donors 0
- XLogP
- 4.1
- TPSA
- 75.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 37
SMILES CC1=C(N(N=N1)C)C2=CC3=C(C4=C(N3[C@@H](C5CCOCC5)C6=CC=CC=C6)C=C7C(=C4)C=NN7C)N=C2
Computed descriptors from PubChem (CID 137448679), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il