Loading...
Chemical structure of Aplaviroc hydrochloride

GC62610

Aplaviroc hydrochloride

Also known as 4-[4-[[(3R)-1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl]methyl]phenoxy]benzoic acid;hydrochloride

Aplaviroc (AK 602) hydrochloride, a SDP derivative, is a CCR5 antagonist, with IC50s of 0·1-0·4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW

ChemicalCAS461023-63-2MW614.17FormulaC33H44ClN3O6
CAS number
461023-63-2
Molecular weight
614.17
Formula
C33H44ClN3O6
Solubility
DMSO ： 500 mg/mL (814·11 mM; Need ultrasonic)
InChIKey
QNNBMSGFNQRUEH-PQQSRXGVSA-N
Catalogue number
GC62610
Brand
GLPBIO
Computed properties PubChem CID 6918686 · TPSA 119 Ų · H-bond donors 4 · H-bond acceptors 7
TPSA
119 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
10
Heavy atoms
43

SMILES CCCCN1C(=O)[C@H](NC(=O)C12CCN(CC2)CC3=CC=C(C=C3)OC4=CC=C(C=C4)C(=O)O)[C@@H](C5CCCCC5)O.Cl

Computed descriptors from PubChem (CID 6918686), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.