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Chemical structure of hnRNPK-IN-1

GC62594

hnRNPK-IN-1

Also known as (E)-1-(4-methoxyphenyl)-3-(4-morpholin-4-yl-6-nitroquinolin-2-yl)prop-2-en-1-one

hnRNPK-IN-1 is a heterogeneous nuclear ribonucleoprotein K (hnRNPK) binding ligand with Kd values of 4·6 μM and 2·6 μM measured with SPR and MST, respectively· hnRNPK-IN-1 inhibits c-myc transcription by disrupting the binding of hnRNPK and c-myc promoter· hnRNPK-IN-1 induces Hela cells apoptosis and has strongly anti-tumor activities

ChemicalCAS2313528-04-8MW419.43FormulaC23H21N3O5
CAS number
2313528-04-8
Molecular weight
419.43
Formula
C23H21N3O5
Solubility
DMSO ： 5 mg/mL (11·92 mM; ultrasonic and warming and heat to 80°C)
InChIKey
PFTIJUIEMIEMQH-RUDMXATFSA-N
Catalogue number
GC62594
Brand
GLPBIO
Computed properties PubChem CID 155977671 · XLogP 3.5 · TPSA 97.5 Ų · H-bond donors 0
XLogP
3.5
TPSA
97.5 Ų
H-bond donors
0
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
31

SMILES COC1=CC=C(C=C1)C(=O)/C=C/C2=CC(=C3C=C(C=CC3=N2)[N+](=O)[O-])N4CCOCC4

Computed descriptors from PubChem (CID 155977671), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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