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Chemical structure of Sivopixant

GC62560

Sivopixant

Also listed as (E/Z)-Sivopixant

(E/Z)-Sivopixant ((E/Z)-S-600918) is a potent P2X3 receptor antagonist with an IC50 of 4 nM

ChemicalCAS1640808-39-4MW507.93FormulaC25H22ClN5O5
CAS number
1640808-39-4
Molecular weight
507.93
Formula
C25H22ClN5O5
Solubility
DMSO : 100 mg/mL (196·88 mM; Need ultrasonic)
InChIKey
SKZQFKBIJUXXCG-INIZCTEOSA-N
Catalogue number
GC62560
Brand
GLPBIO
Computed properties PubChem CID 117752163 · XLogP 3.8 · TPSA 124 Ų · H-bond donors 2
XLogP
3.8
TPSA
124 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
36

SMILES C[C@@H](CN1C(=O)N=C(N(C1=O)CC2=CC=C(C=C2)Cl)NC3=CC=C(C=C3)OC4=CC=CC=N4)C(=O)O

Computed descriptors from PubChem (CID 117752163), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.