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Chemical structure of UNC5293

GC62516

UNC5293

Also known as (2,6-dimethyl-4-pyridinyl)-[4-[7-(4-hydroxycyclohexyl)-2-[[(2S)-pentan-2-yl]amino]pyrrolo[2,3-d]pyrimidin-5-yl]piperidin-1-yl]methanone

UNC5293 is a MERTK-selective and potent inhibitor (Ki=190 pM)· UNC5293 inhibits MERTK (IC50=0·9 nM) and is more selective over Axl, Tyro3 and Flt3· UNC5293 exhibits excellent mouse PK properties and is used for bone marrow leukemia research

ChemicalCAS2226789-82-6MW518.69FormulaC30H42N6O2
CAS number
2226789-82-6
Molecular weight
518.69
Formula
C30H42N6O2
Solubility
DMSO ： 100 mg/mL (192·79 mM; Need ultrasonic)
InChIKey
MSWOWUREQODTRO-CCYWVKEMSA-N
Catalogue number
GC62516
Brand
GLPBIO
Computed properties PubChem CID 146403042 · XLogP 4.6 · TPSA 96.2 Ų · H-bond donors 2
XLogP
4.6
TPSA
96.2 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
38

SMILES CCC[C@H](C)NC1=NC=C2C(=CN(C2=N1)C3CCC(CC3)O)C4CCN(CC4)C(=O)C5=CC(=NC(=C5)C)C

Computed descriptors from PubChem (CID 146403042), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.