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Chemical structure of CFTR corrector 6

GC62510

CFTR corrector 6

Also known as 4-amino-7-[[1-(2-fluorophenyl)pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)pyrimidin-5-yl]pyrrolo[2,3-d]pyrimidine-6-carbonitrile

CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR)

ChemicalCAS2226970-01-8MW479.39FormulaC22H13F4N9
CAS number
2226970-01-8
Molecular weight
479.39
Formula
C22H13F4N9
Solubility
DMSO ： 100 mg/mL (208·60 mM; Need ultrasonic)
InChIKey
LSTMAJPRFFZYIT-UHFFFAOYSA-N
Catalogue number
GC62510
Brand
GLPBIO
Computed properties PubChem CID 134518643 · XLogP 2.8 · TPSA 124 Ų · H-bond donors 1
XLogP
2.8
TPSA
124 Ų
H-bond donors
1
H-bond acceptors
11
Rotatable bonds
4
Heavy atoms
35

SMILES C1=CC=C(C(=C1)N2C=C(C=N2)CN3C(=C(C4=C(N=CN=C43)N)C5=CN=C(N=C5)C(F)(F)F)C#N)F

Computed descriptors from PubChem (CID 134518643), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.