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Chemical structure of OBI-3424

GC62501

OBI-3424

Also known as 3-[5-[(1R)-1-[bis(aziridin-1-yl)phosphoryloxy]ethyl]-2-nitrophenoxy]-N,N-dimethylbenzamide

OBI-3424 (TH-3424) is a prodrug that is selectively converted by AKR1C3 (aldo-keto reductase 1C3) to a potent DNA-alkylating agent· OBI-3424 can be used for hepatocellular carcinoma, castrate-resistant prostate cancer, and acute lymphoblastic leukemia (ALL) research

ChemicalCAS2097713-68-1MW460.42FormulaC21H25N4O6P
CAS number
2097713-68-1
Molecular weight
460.42
Formula
C21H25N4O6P
Solubility
DMSO ： 50 mg/mL (108·60 mM; Need ultrasonic)
InChIKey
NWGZZGNICQFUHV-OAHLLOKOSA-N
Catalogue number
GC62501
Brand
GLPBIO
Computed properties PubChem CID 126961329 · XLogP 2.2 · TPSA 108 Ų · H-bond donors 0
XLogP
2.2
TPSA
108 Ų
H-bond donors
0
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
32

SMILES C[C@H](C1=CC(=C(C=C1)[N+](=O)[O-])OC2=CC=CC(=C2)C(=O)N(C)C)OP(=O)(N3CC3)N4CC4

Computed descriptors from PubChem (CID 126961329), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.