GC62498
BTK inhibitor 17
Also known as 4-amino-3-(4-phenoxyphenyl)-1-[(3R)-1-prop-2-enoylpiperidin-3-yl]-6H-pyrazolo[4,5-d]pyridazin-7-one
BTK inhibitor 17 is a potent and orally active irreversible BTK inhibitor with an IC50 of 2·1 nM
ChemicalCAS1858206-76-4MW456.5FormulaC25H24N6O3
- CAS number
- 1858206-76-4
- Molecular weight
- 456.5
- Formula
- C25H24N6O3
- Solubility
- DMSO ： 100 mg/mL (219·06 mM; Need ultrasonic)
- InChIKey
- QUYXPVXTKPTPCA-QGZVFWFLSA-N
- Catalogue number
- GC62498
- Brand
- GLPBIO
Computed properties PubChem CID 118649285 · XLogP 2.5 · TPSA 115 Ų · H-bond donors 2
- XLogP
- 2.5
- TPSA
- 115 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 34
SMILES C=CC(=O)N1CCC[C@H](C1)N2C3=C(C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)C(=NNC3=O)N
Computed descriptors from PubChem (CID 118649285), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il