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Chemical structure of BMS-986202

GC62491

BMS-986202

Also known as 6-(cyclopropanecarbonylamino)-4-[3-(5-fluoropyrimidin-2-yl)-2-methoxyanilino]-N-(trideuteriomethyl)pyridine-3-carboxamide

BMS-986202 is a potent, selective and orally active Tyk2 inhibitor that binds to Tyk2 JH2 with an IC50 of 0·19 nM and a Ki of 0·02 nM

ChemicalCAS1771691-34-9MW439.46FormulaC22H18D3FN6O3
CAS number
1771691-34-9
Molecular weight
439.46
Formula
C22H18D3FN6O3
Solubility
DMSO ： 250 mg/mL (568·88 mM; Need ultrasonic)
InChIKey
BBRMAVGRWHNAIG-FIBGUPNXSA-N
Catalogue number
GC62491
Brand
GLPBIO
Computed properties PubChem CID 155981972 · XLogP 2.2 · TPSA 118 Ų · H-bond donors 3
XLogP
2.2
TPSA
118 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
32

SMILES [2H]C([2H])([2H])NC(=O)C1=CN=C(C=C1NC2=CC=CC(=C2OC)C3=NC=C(C=N3)F)NC(=O)C4CC4

Computed descriptors from PubChem (CID 155981972), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.