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Chemical structure of CXCR2-IN-2

GC62475

CXCR2-IN-2

Also known as 1-[4-chloro-2-hydroxy-3-[(3S)-3-methyloxolan-3-yl]sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea

CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist (IC50=5·2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively)

ChemicalCAS1838123-21-9MW414.9FormulaC18H23ClN2O5S
CAS number
1838123-21-9
Molecular weight
414.9
Formula
C18H23ClN2O5S
Solubility
DMSO ： 240 mg/mL (578·45 mM; Need ultrasonic)
InChIKey
DNXKACKCTLURQN-ACJLOTCBSA-N
Catalogue number
GC62475
Brand
GLPBIO
Computed properties PubChem CID 100951623 · XLogP 2.2 · TPSA 113 Ų · H-bond donors 3
XLogP
2.2
TPSA
113 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
27

SMILES CC1=CCC[C@H]1NC(=O)NC2=C(C(=C(C=C2)Cl)S(=O)(=O)[C@]3(CCOC3)C)O

Computed descriptors from PubChem (CID 100951623), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.