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Chemical structure of CD73-IN-4

GC62452

CD73-IN-4

Also known as [(2R,3S,4R,5R)-5-[6-chloro-4-(cyclopentylamino)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethylphosphonic acid

CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor, with an IC50 of 2·6 nM for human CD73

ChemicalCAS2216764-29-1MW463.81FormulaC16H23ClN5O7P
CAS number
2216764-29-1
Molecular weight
463.81
Formula
C16H23ClN5O7P
Solubility
DMSO ： 125 mg/mL (269·51 mM; Need ultrasonic)
InChIKey
IVHVIBKVJIZKOC-RTWAVKEYSA-N
Catalogue number
GC62452
Brand
GLPBIO
Computed properties PubChem CID 135348940 · XLogP -0.6 · TPSA 172 Ų · H-bond donors 5
XLogP
-0.6
TPSA
172 Ų
H-bond donors
5
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
30

SMILES C1CCC(C1)NC2=C3C=NN(C3=NC(=N2)Cl)[C@H]4[C@@H]([C@@H]([C@H](O4)COCP(=O)(O)O)O)O

Computed descriptors from PubChem (CID 135348940), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.