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Chemical structure of Casein Kinase inhibitor A51

GC62442

Casein Kinase inhibitor A51

Also known as 4-N-[5-chloro-4-[5-(cyclopropylmethyl)-1-methylpyrazol-4-yl]pyrimidin-2-yl]cyclohexane-1,4-diamine

Casein Kinase inhibitor A51 is a potent and orally active casein kinase 1α (CK1α) inhibitor· Casein Kinase inhibitor A51 induces leukemia cell apoptosis, and has potent anti-leukemic activities

ChemicalCAS2079068-74-7MW360.88FormulaC18H25ClN6
CAS number
2079068-74-7
Molecular weight
360.88
Formula
C18H25ClN6
InChIKey
RVZJFCNYSSUDCU-UHFFFAOYSA-N
Catalogue number
GC62442
Brand
GLPBIO
Computed properties PubChem CID 126558497 · XLogP 2.9 · TPSA 81.7 Ų · H-bond donors 2
XLogP
2.9
TPSA
81.7 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
25

SMILES CN1C(=C(C=N1)C2=NC(=NC=C2Cl)NC3CCC(CC3)N)CC4CC4

Computed descriptors from PubChem (CID 126558497), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.