Loading...
Chemical structure of Tovinontrine

GC62409

Tovinontrine

Also known as 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-(oxan-4-yl)-7H-imidazo[1,5-a]pyrazin-8-one

Tovinontrine (IMR-687) is a highly potent and selective phosphodiesterase-9 (PDE9) inhibitor specifically for the treatment of sickle cell disease

ChemicalCAS2062661-53-2MW394.47FormulaC21H26N6O2
CAS number
2062661-53-2
Molecular weight
394.47
Formula
C21H26N6O2
Solubility
DMSO ： 100 mg/mL (253·50 mM; Need ultrasonic)
InChIKey
GWGNPYYVGANHRJ-GDBMZVCRSA-N
Catalogue number
GC62409
Brand
GLPBIO
Computed properties PubChem CID 124220601 · XLogP 0.4 · TPSA 85.2 Ų · H-bond donors 1
XLogP
0.4
TPSA
85.2 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
29

SMILES C[C@@H]1CN(C[C@H]1C2=CN3C(=CN=C3C4CCOCC4)C(=O)N2)CC5=NC=CC=N5

Computed descriptors from PubChem (CID 124220601), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.