Loading...
Chemical structure of Simotinib

GC62385

Simotinib

Also known as N-(3-chloro-4-fluorophenyl)-6-[2-(5,8-dioxa-10-azadispiro[2.0.44.33]undecan-10-yl)ethoxy]-7-methoxyquinazolin-4-amine

Simotinib is a selective, specific, and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC50 of 19·9 nM· Antineoplastic activities

ChemicalCAS944258-89-3MW500.95FormulaC25H26ClFN4O4
CAS number
944258-89-3
Molecular weight
500.95
Formula
C25H26ClFN4O4
InChIKey
OXWUWXCJDBRCCG-UHFFFAOYSA-N
Catalogue number
GC62385
Brand
GLPBIO
Computed properties PubChem CID 16735117 · XLogP 4 · TPSA 78 Ų · H-bond donors 1
XLogP
4
TPSA
78 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
35

SMILES COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCN4CC5(CC5)C6(C4)OCCO6

Computed descriptors from PubChem (CID 16735117), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.